Welcome                                    
                                       To                                       
                                                                                
the Department of Cancer Research (CIRC) - University of Bologna - Italy.       
                                                                                
Director: Prof.Guido Paolucci (tf5a@vm.cineca.it).                              
                                                                                
Address: Centro Interdipartimentale di Ricerche sul Cancro "G.Prodi"            
         Via Massarenti 9, 40138 Bologna                                        
Phone:   +39.51.307532                                                          
FAX:     +39.51.349655                                                          
                                                                                
This gopher is expanding all the time.                                          
                                                                                
Send comments and/or suggestions to:                                            
Roberto Rondelli (tf5boqc1@vm.cineca.it). 



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                               General Information                              
                                                                                
The DEPARTMENT of CANCER RESEARCH (Centro Interdipartimentale di Ricerche       
sul Cancro "Giorgio Prodi" - CIRC) is situated in Bologna's University          
Hospital area and was created in 1984 initially by 6 University's               
Institutions. In 1987 other Institutions were admitted, for a total of 17.      
                                                                                
The aim of this Department is to manage Oncological researches and              
to assure continuous information among different Institutions                   
whit similar activities.                                                        
                                                                                
This Department, actually directed by Prof.Guido Paolucci, was created          
by the will of Prof.Giorgio Prodi and his conviction that Oncology has          
to be characterized by a close interaction between biology and clinics.         
                                                                                
As of October 1, 1993, the Department's staff consists of 73                    
researchers, belong to 5 University's Departments:                              
                                                                                
 - Experimental Pathology                                                       
 - Biochemistry                                                      
 - Chemistry                                                                    
 - Psychology                                                                   
 - Pharmacology                                                                 
                                                                                
 and 12 Medicine and Surgery Institutes:                                        
                                                                                
 - Pathological Anatomy and Histology                                           
 - Cancerology                                                                  
 - Surgery Clinic and Hearth Surgery-II                                         
 - General Surgery Clinic and Therapy                                           
 - Medical Clinic and Gastroenterology                                          
 - Orthopedic Clinic-I                                                          
 - Obstetric and Gynecology Clinic-II                                           
 - Pediatric Clinic-III                                                         
 - Hematology                                                                   
 - Histology and Embryology                                                     
 - Electronic Microscopy Clinic                                                 
 - Radiotherapy                          
                                                                                
General support for Department activities consist of 1800 millions of           
Italian Lire (1,2 millions $) per year, from research's agreements.             
Department's office consists of 120 sqm divided in laboratories and             
secretaries' office and is located                                              
in Pathological Anatomy's and Histology's building.                             
                                                                                
Research at the Department can be divided into 2 main categories:               
clinical and biological.                                                        
                                                                                
In CLINICAL field, these are the main investigation topics:                     
                                                                                
- Combined treatment of localized Osteosarcoma                                  
- Cell proliferation markers in Thyroid tumors                                  
- In vivo Immune-toxic Therapy in Lymph-proliferative syndromes                 
- Phenotypical characterization as guide for therapy in Lymphomas               
- Prevention of Colon-Rectal Cancer in Ulcerous Colitis                         
- Multi-disciplinary therapeutic strategy in Ewing's Sarcoma 
- Molecular diagnosis and monitoring of Minimal Residual Disease in             
  Chronic Myeloid Leukemia                                                      
- Cell proliferation in prognosis of Breast Cancer                              
                                                                                
In BIOLOGICAL field, these are the main investigation topics:                   
                                                                                
- Relationship between extra-cell matrix and tumoral cells                      
- Pharmacological study on cell cultures of Osteosarcoma                        
- Characterization of cell lines of Medulloblastoma                             
- Phenotypic and Genotypic prognostic factors and chemosensitivity              
  in Neuroblastoma                                                              
- In vitro growth control of leukemic blasts                                    
- Punctiform mutations identification in Gs protein in Tyroid Cancer            
- Cancer risk evaluation by new substances utilization in Industry and          
  Agriculture                                                                   
- Phenotypic modulation of extra-cell matrix in neoplastic progression          
- Study on gene containing homeobox sequences in growth and                     
  differentiation in primitive Central Nervous System Tumors 
                                                                                
Another important activity is devoted to the management and the analysis        
of clinical trials Data of the National Task Force for Pediatric Oncology       
(Forza Operativa Nazionale di Oncologia Pediatrica - FONOP) by FONOP            
Operation Office's staff. 

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List of partecipating Institutions (members,addresses and phone numbers)        
                                                                                
                                                                                
Institutions:                                         Members:                  
(address and phone number)                                                      
                                                                                
Istituto di Anatomia Patologica                 Prof.Vincenzo Eusebi            
V.Massarenti,9 - 40138 Bologna -                Prof.Antonio M.Mancini          
tel.:+39.51.391540                              Prof.Alessandro Piccaluga       
                                                Prof.F.Walter Grigioni          
                                                Prof.Paolo Scarani              
                                                Dott.Felice Giangaspero         
                                                                                
Istituto di Cancerologia                        Prof.Sandro Grilli              
V.Filopanti,22 - 40126 Bologna -                Prof.Paola Rocchi               
tel.:+39.51.243585                              Prof.Paolo Perocco              
                                                Prof.A.Maria Ferreri            
                                                Prof.PierLuigi Lollini          
                                                Dott.Patrizia Nanni 
                                                Dott.Carla De Giovanni          
                                                Dott.Mario Mazzullo             
                                                                                
Istituto di Ematologia                          Prof.Sante Tura                 
V.Massarenti,9 - 40138 Bologna -                Prof.Stefano Pileri             
tel.:+39.51.390413                              Dott.Mauro Fiacchini            
                                                Dott.Alessandra Santucci        
                                                Dott.Michele Cavo               
                                                                                
Clinica Ortopedica I                            Prof.Mario Campanacci           
V.Pupilli,1 - 40136 Bologna -                   Prof.Armando Giunti             
tel.:+39.51.582388                                                              
                                                                                
Clinica Pediatrica III                          Prof.Guido Paolucci             
V.Massarenti,11 - 40138 Bologna -               Prof.Paolo Paolucci             
tel.:+39.51.347694                              Prof.Vico Vecchi                
                                                Prof.Rosanna Lazzari            
                                                Prof.Massimo Masi  
                                                Prof.Pasquale Rosito            
                                                Dott.Giampaolo Ricci            
                                                Dott.Fernando Specchia          
                                                                                
Istituto di Radioterapia                        Prof.Lucio Babini               
V.Massarenti,9 - 40138 Bologna -                Prof.Carlo Putti                
tel.:+39.51.6365391                             Prof.Ervedo Cecchetti           
                                                                                
Istituto di Clinica Medica                                                      
e Gastroenterologia                             Prof.Luigi Barbara              
V.Massarenti,9 - 40138 Bologna -                                                
tel.:+39.51.6363260                                                             
                                                                                
Istituto Clinica Chirurgica e                   Prof.Giuseppe Gozzetti          
Cardiochirurgia II                              Prof.Antonio Cunsolo            
V.Massarenti,9 - 40138 Bologna -                Prof.Alighieri Mazziotti        
tel.:+39.51.6363361                             Dott.Sandro Mattioli            

Istituto Clinica Ostetrica e                    Prof.Camillo Orlandi            
Ginecologica II                                 Dott.Alberto Marabini           
V.Massarenti,13 - 40138 Bologna -                                               
tel.:+39.51.399520                                                              
                                                                                
Istituto di Clinica Chirurgica                  Prof.Domenico Marrano           
Generale e Terapia Chirurgica                   Prof.Orazio Campione            
V.Massarenti,9 - 40138 Bologna -                Prof.Francesco Minni            
tel.:+39.51.341541                              Prof.Mario Taffurelli           
                                                                                
Istituto di Microscopia                         Prof.Giuseppe Martinelli        
Elettronica Clinica                             Dott.Giovanna Cenacchi          
V.Massarenti,9 - 40138 Bologna -                                                
tel.:+39.51.302874                                                              
                                                                                
                                                                                
List of individual supporters (Institutions,addresses and phone numbers)   
                                                                                
Dipartimento di Farmacologia                    Prof.Giorgio Cantelli Forti     
V.Irnerio,48 - 40126 Bologna -                                                  
tel.:+39.51.243101                                                              
                                                                                
Dipartimento di Patologia                       Prof.Massimo Derenzini          
Sperimentale                                    Prof.Annalisa Pession           
V.S.Giacomo,14 - 40126 Bologna -                Prof.Anna Gasperi Campani       
tel.:+39.51.243042                              Prof.Luigi Fiume                
                                                                                
Istituto di Istologia ed                        Prof.Gian Paolo Bagnara         
Embriologia Sperimentale                                                        
V.Belmeloro,8 - 40126 Bologna -                                                 
tel.:+39.51.244568                                                              
                                                                                
Istituto Clinica Medica e                       Prof.Guido Biasco               
Gastroenterologia                                                               
V.Massarenti,9 - 40138 Bologna -                                                
tel.:+39.51.6364144
                                                                                
Dipartimento di Biochimica                      Prof.Alessandro Bertoluzza      
V.Irnerio,48 - 40126 Bologna -                                                  
tel.:+39.51.243019                                                              
                                                                                
Dipartimento di Chimica"G.Ciamician"            Prof.Maria Antonietta Morelli   
V.Selmi,2 - 40126 Bologna -                                                     
tel.:+39.51.259565                                                              
                                                                                
Dipartimento di Psicologia                      Prof.Renzo Canestrari           
V.le Berti Pichat,5 - 40127 Bologna -           Prof.Francesco Campione         
tel.:+39.51.351330                              Prof.Giancarlo Trombini         
                                                Prof.Giovanni Fava