Welcome To the Department of Cancer Research (CIRC) - University of Bologna - Italy. Director: Prof.Guido Paolucci (tf5a@vm.cineca.it). Address: Centro Interdipartimentale di Ricerche sul Cancro "G.Prodi" Via Massarenti 9, 40138 Bologna Phone: +39.51.307532 FAX: +39.51.349655 This gopher is expanding all the time. Send comments and/or suggestions to: Roberto Rondelli (tf5boqc1@vm.cineca.it). --- General Information The DEPARTMENT of CANCER RESEARCH (Centro Interdipartimentale di Ricerche sul Cancro "Giorgio Prodi" - CIRC) is situated in Bologna's University Hospital area and was created in 1984 initially by 6 University's Institutions. In 1987 other Institutions were admitted, for a total of 17. The aim of this Department is to manage Oncological researches and to assure continuous information among different Institutions whit similar activities. This Department, actually directed by Prof.Guido Paolucci, was created by the will of Prof.Giorgio Prodi and his conviction that Oncology has to be characterized by a close interaction between biology and clinics. As of October 1, 1993, the Department's staff consists of 73 researchers, belong to 5 University's Departments: - Experimental Pathology - Biochemistry - Chemistry - Psychology - Pharmacology and 12 Medicine and Surgery Institutes: - Pathological Anatomy and Histology - Cancerology - Surgery Clinic and Hearth Surgery-II - General Surgery Clinic and Therapy - Medical Clinic and Gastroenterology - Orthopedic Clinic-I - Obstetric and Gynecology Clinic-II - Pediatric Clinic-III - Hematology - Histology and Embryology - Electronic Microscopy Clinic - Radiotherapy General support for Department activities consist of 1800 millions of Italian Lire (1,2 millions $) per year, from research's agreements. Department's office consists of 120 sqm divided in laboratories and secretaries' office and is located in Pathological Anatomy's and Histology's building. Research at the Department can be divided into 2 main categories: clinical and biological. In CLINICAL field, these are the main investigation topics: - Combined treatment of localized Osteosarcoma - Cell proliferation markers in Thyroid tumors - In vivo Immune-toxic Therapy in Lymph-proliferative syndromes - Phenotypical characterization as guide for therapy in Lymphomas - Prevention of Colon-Rectal Cancer in Ulcerous Colitis - Multi-disciplinary therapeutic strategy in Ewing's Sarcoma - Molecular diagnosis and monitoring of Minimal Residual Disease in Chronic Myeloid Leukemia - Cell proliferation in prognosis of Breast Cancer In BIOLOGICAL field, these are the main investigation topics: - Relationship between extra-cell matrix and tumoral cells - Pharmacological study on cell cultures of Osteosarcoma - Characterization of cell lines of Medulloblastoma - Phenotypic and Genotypic prognostic factors and chemosensitivity in Neuroblastoma - In vitro growth control of leukemic blasts - Punctiform mutations identification in Gs protein in Tyroid Cancer - Cancer risk evaluation by new substances utilization in Industry and Agriculture - Phenotypic modulation of extra-cell matrix in neoplastic progression - Study on gene containing homeobox sequences in growth and differentiation in primitive Central Nervous System Tumors Another important activity is devoted to the management and the analysis of clinical trials Data of the National Task Force for Pediatric Oncology (Forza Operativa Nazionale di Oncologia Pediatrica - FONOP) by FONOP Operation Office's staff. -- List of partecipating Institutions (members,addresses and phone numbers) Institutions: Members: (address and phone number) Istituto di Anatomia Patologica Prof.Vincenzo Eusebi V.Massarenti,9 - 40138 Bologna - Prof.Antonio M.Mancini tel.:+39.51.391540 Prof.Alessandro Piccaluga Prof.F.Walter Grigioni Prof.Paolo Scarani Dott.Felice Giangaspero Istituto di Cancerologia Prof.Sandro Grilli V.Filopanti,22 - 40126 Bologna - Prof.Paola Rocchi tel.:+39.51.243585 Prof.Paolo Perocco Prof.A.Maria Ferreri Prof.PierLuigi Lollini Dott.Patrizia Nanni Dott.Carla De Giovanni Dott.Mario Mazzullo Istituto di Ematologia Prof.Sante Tura V.Massarenti,9 - 40138 Bologna - Prof.Stefano Pileri tel.:+39.51.390413 Dott.Mauro Fiacchini Dott.Alessandra Santucci Dott.Michele Cavo Clinica Ortopedica I Prof.Mario Campanacci V.Pupilli,1 - 40136 Bologna - Prof.Armando Giunti tel.:+39.51.582388 Clinica Pediatrica III Prof.Guido Paolucci V.Massarenti,11 - 40138 Bologna - Prof.Paolo Paolucci tel.:+39.51.347694 Prof.Vico Vecchi Prof.Rosanna Lazzari Prof.Massimo Masi Prof.Pasquale Rosito Dott.Giampaolo Ricci Dott.Fernando Specchia Istituto di Radioterapia Prof.Lucio Babini V.Massarenti,9 - 40138 Bologna - Prof.Carlo Putti tel.:+39.51.6365391 Prof.Ervedo Cecchetti Istituto di Clinica Medica e Gastroenterologia Prof.Luigi Barbara V.Massarenti,9 - 40138 Bologna - tel.:+39.51.6363260 Istituto Clinica Chirurgica e Prof.Giuseppe Gozzetti Cardiochirurgia II Prof.Antonio Cunsolo V.Massarenti,9 - 40138 Bologna - Prof.Alighieri Mazziotti tel.:+39.51.6363361 Dott.Sandro Mattioli Istituto Clinica Ostetrica e Prof.Camillo Orlandi Ginecologica II Dott.Alberto Marabini V.Massarenti,13 - 40138 Bologna - tel.:+39.51.399520 Istituto di Clinica Chirurgica Prof.Domenico Marrano Generale e Terapia Chirurgica Prof.Orazio Campione V.Massarenti,9 - 40138 Bologna - Prof.Francesco Minni tel.:+39.51.341541 Prof.Mario Taffurelli Istituto di Microscopia Prof.Giuseppe Martinelli Elettronica Clinica Dott.Giovanna Cenacchi V.Massarenti,9 - 40138 Bologna - tel.:+39.51.302874 List of individual supporters (Institutions,addresses and phone numbers) Dipartimento di Farmacologia Prof.Giorgio Cantelli Forti V.Irnerio,48 - 40126 Bologna - tel.:+39.51.243101 Dipartimento di Patologia Prof.Massimo Derenzini Sperimentale Prof.Annalisa Pession V.S.Giacomo,14 - 40126 Bologna - Prof.Anna Gasperi Campani tel.:+39.51.243042 Prof.Luigi Fiume Istituto di Istologia ed Prof.Gian Paolo Bagnara Embriologia Sperimentale V.Belmeloro,8 - 40126 Bologna - tel.:+39.51.244568 Istituto Clinica Medica e Prof.Guido Biasco Gastroenterologia V.Massarenti,9 - 40138 Bologna - tel.:+39.51.6364144 Dipartimento di Biochimica Prof.Alessandro Bertoluzza V.Irnerio,48 - 40126 Bologna - tel.:+39.51.243019 Dipartimento di Chimica"G.Ciamician" Prof.Maria Antonietta Morelli V.Selmi,2 - 40126 Bologna - tel.:+39.51.259565 Dipartimento di Psicologia Prof.Renzo Canestrari V.le Berti Pichat,5 - 40127 Bologna - Prof.Francesco Campione tel.:+39.51.351330 Prof.Giancarlo Trombini Prof.Giovanni Fava